Hydroxypropylmethylcellulose (HPMC Cellulose)
Product Name: Hydroxypropyl methylcellulose
Synonyms: Hydroxypropylmethylcellulose (HPMC Cellulose)
CAS Number: 9004-65-3
Characteristics: It is white or pale white cellulose powder or particles.
Descriptions and details:
CAS No. 9004-65-3
Hydroxypropylmethylcellulose (HPMC Cellulose) is multifunctional as a lubricant, foam enhancer and stabilizer, thickener, emulsion stabilizer and film former for hair and skin care products.
With its foam enhancing characters, Hydroxypropyl methylcellulose is especially useful in surfactant systems. It will also contribute to the formation of bubble structure, leading to richer, longer lasting lather. This substance has a relatively high tolerance for both salt and alcohol.
Techniques for Dispersion:
The most favored method is to begin by heating about one third of the total formulation H2O to above 75°C. Add Hydroxypropyl methylcellulose to the vortex of agitated and heated H2O. Mix them till all fully dispersed.
Technically, Hydroxypropyl methylcellulose won’t dissolve at this temperature. After complete dispersion, add the remaining water at RT, about 20C or even a little colder. Then let’s continue mixing them for about half an hour after the total solution was cooled to 25°C or even lower temperature.
Proceed with the formulation.
If heating is impossible, it is preferred to slurry the Hydroxypropyl methylcellulose in a non-solvating media, such as glycerin or PEG, then add the slurry to the vortex of vigorously agitated water. Adding HPMC directly to cold water is not preferred, but if necessary, must be done very slowly under vigorous agitation. Expect longer mixing times for complete dissolution.
Indexes of Hydroxypropyl methylcellulose:
Typical Use Rate: 0.5 - 3%
Appearance: Off-white granular powder
Solubility: Soluble in water
Viscosity (2% solution, dry): 7,500 - 14,000 mPa.s
pH: 5.0 - 8.0
Chemical Charge: Nonionic
Country of Origin: China
Shelf Life: 36 Months.
Shipping Information: HS CODE #39123900
Description:
Hydroxypropylmethylcellulose (HPMC Cellulose) is a semisynthetic, inert, viscoelastic polymer used as eye drops, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of commercial products.
As a food additive, Hydroxypropyl methylcellulose is considered to be an emulsifier, thickening and suspending agent, and an alternative to animal gelatin. E Number: E464.
Different types of HPMC Cellulose products have different proportions of Methoxy and Hydroxypropyl. This will affect the thermal gelation temperature of Hydroxypropyl Methyl Cellulose, and other characters.
In food processing industry, HPMC Cellulose has many preferred characteristics. According to the thermal gelation, film-forming, thickening and other properties Hydroxypropyl methylcellulose could be applied to various edible things in order to enhance food’s taste feel. Very popularly, the formulation of bread has about one percent of Hydroxypropyl methylcellulose, and gelation occurs in contact with hot oil. Thus, a protective layer will be generated at the edge of the frying food, which will effectively control fat absorption.
Application of Hydroxypropylmethylcellulose (HPMC Cellulose) in the Construction Industry: This product could work as the water-retaining substance and retarder of cement mortar. It will enable the mortar with some pumping ability. In plaster slurry, gypsum materials, putty powder or other building materials, Hydroxypropyl methylcellulose works as a binder and it will helps improve the spread-ability. Further more, it helps to prolong the operating time.
Application of Hydroxypropyl methylcellulose in PVC: In the production of PVC, this produce will work as a dispersing substance, which is the main added product in the making of PVC.
Medicine, Food Personal Industrial usages:
Because Hydroxypropyl methylcellulose is non-ionic, and in the preparation process can be effectively purified by washing with hot water, it has a very low ash content. This is an important property. Hydroxypropyl methylcellulose is able to fully pass the strict requirements for producing medicine, food, and personal care commodities.
Application Guide for PVC Industry:
In the polymerization process of PVC suspension polymerization system, The use of Hydroxypropyl methylcellulose as a dispersant might improve suspension dispersion properties, could also improve the particle morphology, and enhance the absorption performance on plasticizers.
Application Guide for Building Material Industry:
Hydroxypropylmethylcellulose (HPMC Cellulose) has high water-holding ability. It will help to prolong the working time of mortar, and effectively raise the work efficiency and it is more than good for the mortar to make high mechanical strength during solidification.
In general, Hydroxypropyl methylcellulose is a semi-synthetic polymer which is widely utilized for multiple usages like ophthalmic lubricant, excipient and controlled-delivery constituent in oral medicaments found in various commodities.
Product Properties:
Density 1.39
Hydroxypropyl methylcellulose solubility H2O: 50 mg/mL, clear to very faintly turbid, faintly yellow
Appearance and form: powder
Color” White to cream
Water Solubility: SOLUBLE
Product features:
HPMC Cellulose is propylene glycol ether of methyl cellulose, hydroxypropyl and methyl combine with anhydrous glucose ring by ether bond. It is white or pale white cellulose powder or particles. It will dissolves in cold water while it will not dissolve in hot water. Solubility in organic solvents of Hydroxypropyl methylcellulose is superior than water soluble. It can be dissolved in anhydrous methanol and ethanol solution. This product is also soluble in chlorinated hydrocarbons and ketones in organic solvents. Hydroxypropyl methylcellulose is soluble in water. And its water solution has a surface activity, the formation of the film after drying, heated and cooled, in turn, from the reversible conversion of sol to gel. HPMC Cellulose could be utilized alone in the cold drink. And it could also be applied together with other emulsifier, stabilizer.
HPMC Cellulose and other water-soluble high weight compounds use mixture, become transparent, higher viscosity. The gelation temperature of low viscosity commodities is relatively higher than high viscosity of commodities. Its solution is stable at RT. Most recedntly, Hydroxypropyl methylcellulose has been widely applied in petroleum chemical industry, paper-making, leather, textile-printing and dyeing, pharmaceutical, food, cosmetics and other industries, and as the dispersing agent, thickening agent, adhesive, excipients, capsule, oil resistant coating and packing etc.
Safety Measures/Side Effects:
After many researches on rats, it is suggested that HPMC Cellulose is non-toxic. It is considered to be “safe as cosmetic ingredients in the present practices of use and concentration.” The authorized organizations also consider Hydroxypropyl methylcellulose to be safe for general use. Particularly in food making industry, it is mainly works as an alternative to animal gelatine with the E number, E464.
Hydroxypropyl methylcellulose is a chemically modified cellulose polymer that is off-white in color and considered safe for human consumption. This product is usually utilized as an alternative to gelatin and gluten in vegan-friendly commodities.
Common uses:
HPMC Cellulose could be an Alternative to Gelatin:
It acts as an alternative to gelatin because of its vegetarian source and its physical similarities to gelatin. This is particularly useful when we want to make our own supplements because it is able to help vegetarians and those who have dietary restrictions consume supplements and medications.
HPMC Cellulose an also be Alternative to Gluten:
This product is also thought to be a perfect replacement for gluten in gluten-free food. When baking bread, it controls “both the diffusion and the loss of water from the bread crumb and the interactions between starch and protein macromolecules”. By this way, it will help to make a softer gluten-free bread and reduces staleness during storage.
Other applications: Hydroxypropyl methylcellulose acts as a thickening agent, coating polymer, binder, and bioadhesive in pharmaceutical, food, and industrial productions.
Hydroxypropyl methylcellulose’s performance in Pharmaceuticals:
Supplement capsules, Drug carrier, Coating agent, Emulsifier in ointments, Tabletting agent, Eye drops
Food: Bakery goods, Ice cream; Salad dressing, Sauce mix.
Industrial: Building materials, Ink, Printing and dyeing of textiles, Paper making
